inability to achieve durable pulmonary vein isolation (PVI) remains a major
limitation to catheter ablation for the treatment of atrial fibrillation (AF),
potentially resulting in AF recurrence. In this review, we discuss the research
performed investigating methods to improve lesion permanence for the goal of
durable PVI. Investigations evaluating procedural techniques, various catheters
utilized, adjunctive pharmacologic therapy, and novel energy sources designed
to improve ablation lesion permanence are discussed.
Credits: Darrat Y; Morales G; Shah J; Di Biase L; Natale A; Elayi CS