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Durable Pulmonary Vein Isolation: The Holy Grail of Atrial Fibrillation Ablation

The inability to achieve durable pulmonary vein isolation (PVI) remains a major limitation to catheter ablation for the treatment of atrial fibrillation (AF), potentially resulting in AF recurrence. In this review, we discuss the research performed investigating methods to improve lesion permanence for the goal of durable PVI. Investigations evaluating procedural techniques, various catheters utilized, adjunctive pharmacologic therapy, and novel energy sources designed to improve ablation lesion permanence are discussed.

Credits: Darrat Y; Morales G; Shah J; Di Biase L; Natale A; Elayi CS

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Introduction to AFib
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