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Catheter Ablation for Persistent and Long-Standing Persistent Atrial Fibrillation


Persistent and long-standing persistent atrial fibrillation evolves from complex arrhythmogenic substrate and sources. Multiple studies have shown improved freedom from arrhythmia recurrences if sinus rhythm had been restored during the index ablation; however, such harder procedural endpoint requires laborious stepwise approach almost invariably pursuing non-pulmonary-vein sources. Longer-term conversion of persistent atrial fibrillation into sinus rhythm is associated with significant improvement in major indices of hemodynamic and functional status; these indices also represent major predictors of cardiovascular mortality. Optimal ablation techniques and strategies preserving most of the individual potential for functional improvement need to be established.

Credits: Martin Fiala



Biosense Webster
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Introduction to AFib
Ablation Specialist

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