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Impact of Alcohol Consumption on Atrial Fibrillation Outcomes Following Pulmonary Vein Isolation

Background: Moderate to heavy alcohol use has been shown to be associated with increased atrial fibrillation (AF) incidence. However, the relationship between alcohol use and AF recurrence after pulmonary vein isolation (PVI) is not well known. Objective: We sought to study the impact of different alcohol consumption levels on outcomes after AF ablation. Methods: A retrospective analysis was performed of 226 consecutive patients undergoing first time PVI for AF. Clinical data were collected including alcohol intake classified into 3 groups: none-rare (< 1 drink/ week), moderate (1-7 drinks/ week), and heavy (> 7 drinks/ week). Patients were followed for recurrences within the first 3 months (blanking period; early recurrence) and after 3 months up to 1 year (late recurrence) after the ablation. Results: Paroxysmal and persistent AF had early recurrence rates of 29.1% and 32.2%, and late recurrence rates of 30.2% and 44.1%, respectively. The none-rare alcohol group had a higher frequency of diabetes mellitus (p=0.007). Neither moderate or heavy alcohol consumption, in reference to the none-rare group, was significantly predictive of early or late AF recurrence on adjusted multivariate logistic regression analysis (p>0.05). Conclusion: Despite known associations between alcohol and incidence of AF, alcohol consumption is not associated with early or late AF recurrence after PVI in this cohort.

Credits: Waseem Y. Barham, MD, William H. Sauer, MD, FHRS, Blake Fleeman, MD, Michael Brunnquell, MD, Wendy Tzou, MD, FHRS, Ryan Aleong, MD, FHRS, Joseph Schuller, MD, FHRS, Matthew Zipse, MD, Christine Tompkins, MD, Duy T Nguyen, MD

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