PREDICTION OF CATHETER ABLATION EFFICACY FOR PATIENTS WITH PAROXYSMAL OR PERSISTENT ATRIAL FIBRILLATION

S. Dolginina, S. Garkina, S. Khokhlunov, D. Duplyakov

Cardiology department of Samara Regional Cardiology Center, Samara, Russian Federation

Abstract

Introduction: Catheter ablation is considered to improve symptoms and quality of life for patients with atrial fibrillation (AF) and may be regarded as first-line treatment compared with medical therapy especially in paroxysmal forms.
Methods: We enrolled 148 patients (mean age 52+9.2 years, male 87 (59%)) with paroxysmal (47%) and persistent (53%) AF which underwent radiofrequency ablation (RFA). Follow up period was 5 years.
Results: The majority of patients experienced relapse of AF during the first 6 months after RFA (54 of 77 cases). Significant correlations were obtained between recurrence of arrhythmia and dilation of the left atrium (LA) (r = -0.58, p < 0.001), the patients age (r = 0.66, p < 0.001), antiarrhythmic treatment (r = 0.40, p < 0.001), aortic (r = 0.55, p < 0.001) and mitral regurgitation (r = 0.41, p < 0.001). Logistic regression equation takes the following form: risk of AF recurrence = -14.4+ 0.12*age + 0.21*LA diameter– 0.5*previous antiarrhythmic treatment+ 2.33*aortic regurgitation+ 0.89*mitral regurgitation.
Conclusions: This mathematical model evaluating initial risk of post-operative AF recurrence should be used before RFA to optimize screening of patients with favorable prognosis of sinus rhythm maintenance.